CRISPR is a family of DNA sequence found in the genomes of prokaryotic organisms such as bacteria and arachea. These sequence are derived from fragments of bacteriophages that had previously infected the prokaryote .They are used to detect and destroy DNA from similar bacteriophages during subsequent infections.
A team from university of california berkeley, us developed a techniques using CRISPR to profile cells and rapidly determined all the DNA sequences in the genome that regulate the expression of a specific gene.
"A disease where you might want to use this approach is cancer" ,where we know certain genes that those cancer cell express and need to express in order to service and growth,said associate professor Nicholuslngolia.
This application foe CRISPR technologies in bio medicine are also myriad screens for the discovery of drugs or gene functions in particular new cell lines and animal models diseases,genes therapies for sickle cell anaemia or muscular.
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